Phenytoin intoxication induced by sulthiame in epileptic patients.
نویسندگان
چکیده
Routine estimation of serum phenytoin levels in patients newly admitted to a Special Centre for Epilepsy showed that 40% of those receiving sulthiame in addition to phenytoin had levels in the toxic range. Four long-stay patients became drug intoxicated when sulthiame treatment was started. Sulthiame appears to inhibit the hepatic hydroxylation of phenytoin.
منابع مشابه
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عنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 37 3 شماره
صفحات -
تاریخ انتشار 1974